Molecular characterization of ESBL-producing Escherichia coli isolates from hospital- and community-acquired infections in NW Mexico

Diagn Microbiol Infect Dis. 2017 Jan;87(1):49-52. doi: 10.1016/j.diagmicrobio.2016.10.006. Epub 2016 Oct 7.

Abstract

We investigated the molecular characteristics of ESBL-producing E. coli (ESBL-PEc) isolates from two hospitals and community settings in Ciudad Obregon, Sonora, Mexico. Between 2011 and 2014, thirty-seven ESBL-PEc isolates were collected. The major encoded ESBL was the blaCTX-M-15 gene (97%); followed by 13.5% of the blaSHV-12 gene, and 5.5% encoded the blaTLA-1 gene. The PMQR gene aac(6´)-Ib-cr was detected in 97% of the isolates and the qnrB gene, in one isolate. The ESBL-PEc isolates corresponded to phylogenetic group B2, ST131. Our results highlight the dissemination of ESBL-PEc isolates in northwest Mexico (Ciudad Obregon, Sonora).

Keywords: Hospital and community isolates; PMQR; Quinolone resistance; β-Lactamases.

MeSH terms

  • Community-Acquired Infections / epidemiology
  • Community-Acquired Infections / microbiology*
  • Cross Infection / epidemiology
  • Cross Infection / microbiology*
  • Escherichia coli / classification
  • Escherichia coli / enzymology
  • Escherichia coli / genetics
  • Escherichia coli / isolation & purification*
  • Escherichia coli Infections / epidemiology
  • Escherichia coli Infections / microbiology*
  • Genes, Bacterial*
  • Genotype*
  • Humans
  • Mexico / epidemiology
  • Phylogeny
  • beta-Lactamases / genetics
  • beta-Lactamases / metabolism*

Substances

  • beta-Lactamases