Functionalization of 2D transition metal dichalcogenides for biomedical applications

Mater Sci Eng C Mater Biol Appl. 2017 Jan 1;70(Pt 2):1095-1106. doi: 10.1016/j.msec.2016.03.039. Epub 2016 Mar 15.

Abstract

Recent research has revealed a gamut of interesting properties present in layered two-dimensional (2D) transition metal dichalcogenides (TMDCs) such as photoluminescence, comparatively high electron mobility, flexibility, mechanical strength and relatively low toxicity. The large surface to area ratio inherent in these materials also allows easy functionalization and maximal interaction with the external environment. Due to its unique physical and chemical properties, much work has been done in tailoring TMDCs through chemical functionalization for use in a diverse range of biomedical applications as biosensors, drug delivery carriers or even as therapeutic agents. In this review, current progress on the different types of TMDC functionalization for various biological applications will be presented and its future outlook will be discussed.

Keywords: Biomaterials; Biomedical applications; Biosensor; Functionalization; Transition metal dichalcogenides; Two-dimensional.

Publication types

  • Review

MeSH terms

  • Biocompatible Materials / chemical synthesis
  • Biocompatible Materials / chemistry
  • Biomedical Technology / methods*
  • Chalcogens / chemical synthesis
  • Chalcogens / chemistry*
  • Transition Elements / chemistry*

Substances

  • Biocompatible Materials
  • Chalcogens
  • Transition Elements