Shape of Thyroid Cartilage Influences Outcome of Montgomery Medialization Thyroplasty: A Gender Issue

J Voice. 2017 Mar;31(2):245.e3-245.e8. doi: 10.1016/j.jvoice.2016.08.010. Epub 2016 Oct 18.

Abstract

Objective: This study aimed to determine whether the shape of the thyroid cartilage and gender influence voice outcomes after a Montgomery thyroplasty implant system (MTIS).

Methods: A retrospective cohort study was performed on 20 consecutive patients who underwent MTIS. Voice outcome variables were the relative decrease in Voice Handicap Index (%) and the absolute increase in maximum phonation time (MPT) (in seconds). Material variables were the angle between the thyroid cartilage laminae (α-angle), the size of the prosthesis, and a combination of both (the α-ratio). Continuous variables were analyzed using medians and were compared between groups using the Mann-Whitney U test. Factors associated with the outcome variables were assessed by multivariable linear regression. A Pearson coefficient was calculated between material variables.

Results: The absolute increase in MPT between the pre- and postoperative period was significantly different between men and women, with a median absolute increase of 11.0 seconds for men and of 1.3 seconds for women (P < 0.001). A strong inverse correlation between the α-ratio and the absolute increase in MPT is observed in all patients, with a Pearson correlation coefficient R = -0.769 (P < 0.001). No factors were significantly associated with the relative Voice Handicap Index decrease in univariable or multivariable analyses. A better Pearson coefficient between the α-angle and the prosthesis size was found for females (0.8 vs 0.71).

Conclusion: The MTIS is a good thyroplasty modality for male patients, but inadequate design of MTIS female implants leads to poor MPT outcomes. This represents a gender issue that needs to be further studied and eventually tackled.

Keywords: Gender; Larynx anatomy; Montgomery implant; Thyroplasty; Voice outcome.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Disability Evaluation
  • Dysphonia / etiology
  • Dysphonia / physiopathology
  • Female
  • Humans
  • Laryngoplasty / adverse effects
  • Laryngoplasty / instrumentation*
  • Male
  • Middle Aged
  • Phonation*
  • Predictive Value of Tests
  • Prosthesis Design*
  • Prosthesis Implantation / adverse effects
  • Prosthesis Implantation / instrumentation*
  • Retrospective Studies
  • Sex Factors
  • Surveys and Questionnaires
  • Thyroid Cartilage / diagnostic imaging
  • Thyroid Cartilage / physiopathology
  • Thyroid Cartilage / surgery*
  • Time Factors
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Vocal Cord Paralysis / diagnosis
  • Vocal Cord Paralysis / physiopathology
  • Vocal Cord Paralysis / surgery*
  • Voice Quality*