Ruthenium(ii)-catalyzed C-H functionalizations on benzoic acids with aryl, alkenyl and alkynyl halides by weak-O-coordination

Chem Commun (Camb). 2016 Nov 18;52(89):13171-13174. doi: 10.1039/c6cc07773k. Epub 2016 Oct 21.

Abstract

C-H arylations of weakly coordinating benzoic acids were achieved by versatile ruthenium(ii) catalysis with ample substrate scope. Thus, user-friendly ruthenium(ii) biscarboxylate complexes modified with tricyclohexylphosphine enabled C-H functionalizations with aryl electrophiles. The unique versatility of the ruthenium(ii) catalysis manifold was reflected by facilitating effective C-H activations with aryl, alkenyl and alkynyl halides.