Increased Community-Associated Infections Caused by Panton-Valentine Leukocidin-Negative MRSA, Shanghai, 2005-2014

Emerg Infect Dis. 2016 Nov;22(11):1988-1991. doi: 10.3201/eid2211.160587.

Abstract

During 2005-2014, community-associated methicillin-resistant Staphylococcus aureus infections increased in Shanghai, China. Most infections were caused by sequence type 59 S. aureus that lacked Panton-Valentine leukocidin. This finding challenges the notion that Panton-Valentine leukocidin is necessary for epidemiologic success of community-associated methicillin-resistant S. aureus.

Keywords: China; MRSA; PVL; Panton-Valentine leukocidin; Shanghai; bacteria; community-acquired infections; community-associated infections; methicillin-resistant Staphylococcus aureus.

Publication types

  • Historical Article

MeSH terms

  • Bacterial Toxins / genetics*
  • China / epidemiology
  • Community-Acquired Infections / epidemiology*
  • Community-Acquired Infections / history
  • Community-Acquired Infections / microbiology*
  • Cross Infection / epidemiology
  • Cross Infection / microbiology
  • Exotoxins / genetics*
  • History, 21st Century
  • Humans
  • Leukocidins / genetics*
  • Methicillin-Resistant Staphylococcus aureus / classification
  • Methicillin-Resistant Staphylococcus aureus / genetics*
  • Methicillin-Resistant Staphylococcus aureus / isolation & purification
  • Staphylococcal Infections / epidemiology*
  • Staphylococcal Infections / history
  • Staphylococcal Infections / microbiology*

Substances

  • Bacterial Toxins
  • Exotoxins
  • Leukocidins
  • Panton-Valentine leukocidin