Data on common variants associated with coronary artery disease/myocardial infarction in ethnic Arabs

Salma M Wakil; Ramesh Ram; Nzioka P Muiya; Munish Mehta; Editha Andres; Nejat Mazhar; Batoul Baz; Samya Hagos; Maie Alshahid; Brian F Meyer; Grant Morahan; Nduna Dzimiri

doi:10.1016/j.dib.2016.02.010

Data on common variants associated with coronary artery disease/myocardial infarction in ethnic Arabs

Data Brief. 2016 Feb 9:7:172-176. doi: 10.1016/j.dib.2016.02.010. eCollection 2016 Jun.

Authors

Affiliations

¹ Genetics Department, King Faisal Specialist Hospital and Research Centre, Riyadh, KSA, Saudi Arabia.
² Harry Perkins Institute of Medical Research, University of Western Australia, Australia.
³ King Faisal Heart Institute, King Faisal Specialist Hospital and Research Centre, Riyadh, KSA, Saudi Arabia.

Abstract

The data shows results acquired in a large cohort of 5668 ethnic Arabs involved in a common variants association study for coronary artery disease (CAD) and myocardial infarction (MI) using the Affymetrix Axiom Genotyping platform ("A genome-wide association study reveals susceptibility loci for myocardial infarction/coronary artery disease in Saudi Arabs" Wakil et al. (2015) [1] ). Several loci were described that conferred risk for CAD or MI, some of which were validated in an independent set of samples. Principal Component (PCA) analysis suggested that the Saudi Cohort was close to the CEU and TSI populations, thus pointing to similarity with European populations.