Draft genome sequence of Mycobacterium tuberculosis strain B9741 of Beijing B0/W lineage from HIV positive patient from Siberia

K V Shur; M V Zaychikova; N E Mikheecheva; K M Klimina; O B Bekker; S N Zhdanova; O B Ogarkov; V N Danilenko

doi:10.1016/j.gdata.2016.08.001

Draft genome sequence of Mycobacterium tuberculosis strain B9741 of Beijing B0/W lineage from HIV positive patient from Siberia

Genom Data. 2016 Aug 3:10:61-62. doi: 10.1016/j.gdata.2016.08.001. eCollection 2016 Dec.

Authors

K V Shur¹, M V Zaychikova¹, N E Mikheecheva¹, K M Klimina¹, O B Bekker¹, S N Zhdanova², O B Ogarkov², V N Danilenko¹

Affiliations

¹ Laboratory of Bacterial Genetics, Vavilov Institute of General Genetics (VIGG RAS), Gubkina str. 3, 119991 Moscow, Russia.
² Scientific Centre for Family Health and Human Reproduction Problems (SCFHHRP), Irkutsk, Russia.

Abstract

We report a draft genome sequence of Mycobacterium tuberculosis strain B9741 belonging to Beijing B0/W lineage isolated from a HIV patient from Siberia, Russia. This clinical isolate showed MDR phenotype and resistance to isoniazid, rifampin, streptomycin and pyrazinamide. We analyzed SNPs associated with virulence and resistance. The draft genome sequence and annotation have been deposited at GenBank under the accession NZ_LVJJ00000000.

Keywords: Beijing lineage; HIV; Mycobacterium tuberculosis; Virulence; draft genome sequencing.