Congenital insensitivity to pain and anhydrosis due to a rare mutation and that is complicated by inflammatory bowel disease and amyloidosis: a case report

Faris G Bakri; Ayman Wahbeh; Awni Abu Sneina; Ali Al Khader; Fatima Obeidat; Izzat AlAwwa; Maryam Buni; Chang-Seok Ki; Amira Masri

doi:10.1002/ccr3.689

Congenital insensitivity to pain and anhydrosis due to a rare mutation and that is complicated by inflammatory bowel disease and amyloidosis: a case report

Clin Case Rep. 2016 Sep 12;4(10):997-1000. doi: 10.1002/ccr3.689. eCollection 2016 Oct.

Authors

Faris G Bakri¹, Ayman Wahbeh¹, Awni Abu Sneina¹, Ali Al Khader², Fatima Obeidat², Izzat AlAwwa¹, Maryam Buni³, Chang-Seok Ki⁴, Amira Masri⁵

Affiliations

¹ Department of Medicine School of Medicine The University of Jordan Amman Jordan.
² Department of Laboratory Medicine Division of Pathology Jordan University Hospital The University of Jordan Amman Jordan.
³ Internal Medicine Residency Training Program Department of Internal Medicine University of Texas Medical School at Houston Houston Texas USA.
⁴ Department of Laboratory Medicine & Genetics Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea.
⁵ Department of Pediatrics Division of Child Neurology Jordan University Hospital The University of Jordan Amman Jordan.

Abstract

Patients with congenital insensitivity to pain and anhydrosis syndrome are at risk for renal amyloidosis and inflammatory bowel disease. Physicians caring for such patients should be aware of these complications.

Keywords: Amyloidosis; Jordan; NTRK1 gene; congenital insensitivity to pain and anhydrosis; hereditary sensory and autonomic neuropathy; inflammatory bowel disease; nephrotic syndrome; osteomyelitis.

Publication types

Case Reports