Presentation to delivery interval in women with early preterm delivery presenting with preterm labor: the effect of gestational age

J Matern Fetal Neonatal Med. 2017 Oct;30(19):2356-2361. doi: 10.1080/14767058.2016.1248934. Epub 2016 Nov 2.

Abstract

Background: To evaluate the association between gestational age at presentation and interval to delivery in women with early spontaneous preterm delivery (PTD).

Methods: A retrospective cohort study of women who presented with threatened preterm labor (tPTL) and intact membranes and had a spontaneous PTD <34 weeks in a university-affiliated hospital (2009-2015). The interval from presentation to delivery was compared between different gestational age subgroups.

Results: Of 67 550 deliveries during the study period, 252 met inclusion criteria. This cohort was divided to three gestational age subgroups at presentation: 24-286/7 weeks (n = 83), 29-316/7 weeks (n = 61) and 32-336/7 weeks (n = 108). Median time from presentation to delivery was 24.5 h. An inverse relation was observed between gestational age at presentation and admission-delivery interval (group A: 74.7 h, group B: 21.0 h, group C: 14.0 h, p < 0.001).

Conclusion: Gestational age at presentation is inversely related to admission-delivery interval in women with tPTL and intact membranes.

Keywords: Preterm delivery; gestational age; interval to delivery; threatened preterm labor.

MeSH terms

  • Adult
  • Female
  • Fetal Membranes, Premature Rupture / epidemiology*
  • Gestational Age*
  • Humans
  • Israel / epidemiology
  • Pregnancy
  • Premature Birth / epidemiology*
  • Retrospective Studies
  • Young Adult

Supplementary concepts

  • Preterm Premature Rupture of the Membranes