Effect of culture conditions on metabolites produced by the crinoid-derived fungus Aspergillus ruber 1017

Nat Prod Res. 2017 Jun;31(11):1299-1304. doi: 10.1080/14786419.2016.1244200. Epub 2016 Oct 18.

Abstract

Two different culture media were used to cultivate fungus Aspergillus ruber 1017 and resulted in the isolation of one new compound (1) and 23 known compounds (2-24). Alkaloids were the major metabolite in soybean medium instead of anthraquinone from rice medium. The structures of these compounds were elucidated according to spectroscopic analysis and comparison with reported data. Antibacterial activities of compounds 1-12 against 12 aquatic bacteria were evaluated.

Keywords: Aspergillus ruber; Crinoid; culture conditions.

MeSH terms

  • Alkaloids / isolation & purification
  • Alkaloids / metabolism
  • Anthraquinones / metabolism
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / isolation & purification
  • Anti-Bacterial Agents / pharmacology
  • Aspergillus / chemistry
  • Aspergillus / metabolism*
  • Bacteria / drug effects
  • Culture Media / pharmacology*
  • Glycine max / metabolism
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Oryza / metabolism
  • Spectrum Analysis

Substances

  • Alkaloids
  • Anthraquinones
  • Anti-Bacterial Agents
  • Culture Media