Primary monophasic synovial sarcoma of the pleura: Neoadjuvant chemotherapy followed by complete resection

Ramiro G M Silva; Jefferson L Gross; Rodrigo A Silva; Fabio J Haddad; Riad N Younes; Vasco M Cruz; Antonio B M Avertano-Rocha

doi:10.1111/j.1759-7714.2010.00019.x

Primary monophasic synovial sarcoma of the pleura: Neoadjuvant chemotherapy followed by complete resection

Thorac Cancer. 2010 Sep;1(3):95-101. doi: 10.1111/j.1759-7714.2010.00019.x.

Authors

Ramiro G M Silva¹, Jefferson L Gross¹, Rodrigo A Silva¹, Fabio J Haddad¹, Riad N Younes¹, Vasco M Cruz¹, Antonio B M Avertano-Rocha¹

Affiliation

¹ Surgical Oncology, A.C. Camargo Hospital, São Paulo, Brazil Department of Thoracic Surgery, A.C. Camargo Hospital, São Paulo, Brazil.

PMID: 27755799
DOI: 10.1111/j.1759-7714.2010.00019.x

Abstract

We describe a rare case of primary pleural synovial sarcoma in a 27-year-old man with a 4-month history of dry cough and left-sided chest pain. A CT scan showed a large cystic mass in the left pleural cavity. The patient underwent two video-assisted thoracoscopic biopsies and the diagnosis of synovial sarcoma of the pleura was established. After neoadjuvant chemotherapy, which resulted in a partial response, the tumor was completely resected with extrapleural pneumonectomy. Pathological findings showed less than 5% of viable cancer and free surgical margins. The patient is clinically well 24 months after surgery, with no evidence of recurrent disease.

Keywords: Immunochemistry; pleura; pneumonectomy; synovial sarcoma.

Publication types

Review