Chemical Components and Pharmacological Activities of Terpene Natural Products from the Genus Paeonia

Molecules. 2016 Oct 13;21(10):1362. doi: 10.3390/molecules21101362.

Abstract

Paeonia is the single genus of ca. 33 known species in the family Paeoniaceae, found in Asia, Europe and Western North America. Up to now, more than 180 compounds have been isolated from nine species of the genus Paeonia, including terpenes, phenols, flavonoids, essential oil and tannins. Terpenes, the most abundant naturally occurring compounds, which accounted for about 57% and occurred in almost every species, are responsible for the observed in vivo and in vitro biological activities. This paper aims to give a comprehensive overview of the recent phytochemical and pharmacological knowledge of the terpenes from Paeonia plants, and enlighten further drug discovery research.

Keywords: Genus Paeonia; chemical components; pharmacological activities; terpene.

Publication types

  • Review

MeSH terms

  • Anesthetics / chemistry
  • Anesthetics / pharmacology
  • Animals
  • Anti-Inflammatory Agents / chemistry
  • Anti-Inflammatory Agents / pharmacology
  • Anticoagulants / chemistry
  • Anticoagulants / pharmacology
  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / pharmacology
  • Antioxidants / chemistry
  • Antioxidants / pharmacology
  • Drug Discovery
  • Humans
  • Hypnotics and Sedatives / chemistry
  • Hypnotics and Sedatives / pharmacology
  • Molecular Structure
  • Paeonia / chemistry*
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology
  • Terpenes / chemistry*
  • Terpenes / pharmacology*

Substances

  • Anesthetics
  • Anti-Inflammatory Agents
  • Anticoagulants
  • Antineoplastic Agents
  • Antioxidants
  • Hypnotics and Sedatives
  • Plant Extracts
  • Terpenes