Giant tubular adenoma with malignancy clinical characteristics in a female teenager: Case report and a review of the literature

Medicine (Baltimore). 2016 Oct;95(40):e4805. doi: 10.1097/MD.0000000000004805.

Abstract

Background: Adenomas of the colon are usually benign tumors which carry a tendency for malignancy. These tumors can be villous, tubular, tubulovillous, or sessile serrated. Those with adenomatous structure can develop malignant characteristics in 1.5% to 9.4% of cases.

Methods: We present a case report of a 16-year-old female adolescent with an adenoma of the descending colon. History revealed prolonged diarrheic syndrome for the past 6 months, repeated headache, and a weight loss of ∼5 kg in the past month. One week before the admission, the patient presented an episode of inferior digestive hemorrhage.

Results: On admission laboratory tests revealed iron deficiency anemia, and a mildly increased erythrocyte sedimentation rate. The abdominal ultrasound revealed an inhomogeneous mass of the descending colon and 2 hyperechoic lesions in the liver. The colonoscopy showed a tumor of the descending colon, a tubular adenoma according to the pathological examination. Additionally, we noted an atypical presentation of the tumor and the signs of mild dysplasia identified at the pathological examination.

Conclusion: Weight loss, bowel transit alterations, loss of appetite, and inferior hemorrhage in an adolescent can be symptoms of a benign or malignant tumor of the colon.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenoma / complications*
  • Adenoma / diagnosis*
  • Adenoma / therapy
  • Adolescent
  • Colonic Neoplasms / complications*
  • Colonic Neoplasms / diagnosis*
  • Colonic Neoplasms / therapy
  • Colonoscopy
  • Female
  • Humans