Methods for Selecting Phage Display Antibody Libraries

Curr Pharm Des. 2016;22(43):6490-6499. doi: 10.2174/1381612822666161007153127.

Abstract

The selection process aims sequential enrichment of phage antibody display library in clones that recognize the target of interest or antigen as the library undergoes successive rounds of selection. In this review, selection methods most commonly used for phage display antibody libraries have been comprehensively described.

Keywords: Phage display; antibody; antigen; epitope..

Publication types

  • Review

MeSH terms

  • Antibodies / chemistry
  • Antibodies / genetics
  • Antibodies / immunology*
  • Antigens / immunology
  • Bacteriophages / genetics*
  • Epitopes / immunology
  • Peptide Library*

Substances

  • Antibodies
  • Antigens
  • Epitopes
  • Peptide Library