Neoatherosclerosis causing occlusive in-stent restenosis: Impact of intracoronary imaging in the intensity of lipid-lowering therapy

Cardiovasc Revasc Med. 2016 Dec;17(8):584-585. doi: 10.1016/j.carrev.2016.09.013. Epub 2016 Sep 30.

Abstract

The unique physical properties of optical coherence tomography (OCT) make it a useful technique in the study of restenosis mechanisms. In fact, OCT is able to differentiate between neointimal proliferation and neoatherosclerosis within the stent. We report a rare case of occlusive neoatherosclerosis presenting beyond one year after a successful drug-eluting stent implantation. The impact of OCT findings in the clinical decision making process is emphasized.

Keywords: In-stent restenosis; Neoatherosclerosis; Optical coherence tomography.

Publication types

  • Case Reports
  • Video-Audio Media

MeSH terms

  • Aged
  • Cardiovascular Agents / administration & dosage
  • Coronary Angiography
  • Coronary Artery Disease / diagnostic imaging
  • Coronary Artery Disease / therapy*
  • Coronary Occlusion / diagnostic imaging
  • Coronary Occlusion / etiology*
  • Coronary Occlusion / therapy
  • Coronary Restenosis / diagnostic imaging
  • Coronary Restenosis / etiology*
  • Coronary Restenosis / therapy
  • Coronary Vessels / diagnostic imaging*
  • Drug-Eluting Stents
  • Humans
  • Hypolipidemic Agents / therapeutic use*
  • Male
  • Percutaneous Coronary Intervention / adverse effects
  • Percutaneous Coronary Intervention / instrumentation*
  • Plaque, Atherosclerotic*
  • Retreatment
  • Sirolimus / administration & dosage
  • Sirolimus / analogs & derivatives
  • Stents*
  • Time Factors
  • Tomography, Optical Coherence
  • Treatment Outcome

Substances

  • Cardiovascular Agents
  • Hypolipidemic Agents
  • umirolimus
  • Sirolimus