Cell Microencapsulation: Dripping Methods

Methods Mol Biol. 2017:1479:43-55. doi: 10.1007/978-1-4939-6364-5_3.

Abstract

Microencapsulation processes may be divided into three steps, namely: incorporation of the bioactive substance in the matrix, dispersion of the matrix in droplets, and conversion in microcapsules. This contribution is focused on the second step and more specifically using the dripping approach to form droplets by extrusion of liquid through a nozzle. Different technologies of dripping are described, using as an example the production of alginate beads.

Keywords: Dripping; Droplet size; Production.

MeSH terms

  • Alginates / chemistry*
  • Algorithms
  • Capsules / chemistry
  • Drug Compounding / instrumentation
  • Drug Compounding / methods*
  • Equipment Design
  • Glucuronic Acid / chemistry
  • Gravitation
  • Hexuronic Acids / chemistry
  • Microspheres
  • Particle Size
  • Static Electricity

Substances

  • Alginates
  • Capsules
  • Hexuronic Acids
  • Glucuronic Acid