Assembly-Induced Thermogenesis of Gold Nanoparticles in the Presence of Alternating Magnetic Field for Controllable Drug Release of Hydrogel

Peng Wang; Jianfei Sun; Zhichao Lou; Fengguo Fan; Ke Hu; Yi Sun; Ning Gu

doi:10.1002/adma.201603632

Assembly-Induced Thermogenesis of Gold Nanoparticles in the Presence of Alternating Magnetic Field for Controllable Drug Release of Hydrogel

Adv Mater. 2016 Dec;28(48):10801-10808. doi: 10.1002/adma.201603632. Epub 2016 Oct 13.

Authors

Peng Wang¹, Jianfei Sun¹, Zhichao Lou^{1

2}, Fengguo Fan^{1

3}, Ke Hu⁴, Yi Sun¹, Ning Gu¹

Affiliations

¹ State Key Laboratory of Bioelectronics, Jiangsu Laboratory for Biomaterials and Devices, Department of Biological Science and Medical Engineering, Southeast University, Nanjing, 210009, P. R. China.
² College of Materials Science and Engineering, Nanjing Forestry University, Nanjing, 210037, P. R. China.
³ Department of Physics, Shangqiu Normal College, Shangqiu, Henan, 476000, P. R. China.
⁴ Department of Biomedical Engineering, Nanjing Medical University, Nanjing, 210029, P. R. China.

PMID: 27735090
DOI: 10.1002/adma.201603632

Abstract

Films of gold nanoparticles are easily fabricated by layer-by-layer assembly. With increasing number of layers a transition of the electric property from insulating to conducting can be achieved. This conductivity leads to controllable thermogenesis of the film, which can be employed for drug release of loaded hydrogels.

Keywords: drug release; gold; hydrogels; nanoparticles.