The CCN Proteins: An Overview

Masaharu Takigawa

doi:10.1007/978-1-4939-6430-7_1

The CCN Proteins: An Overview

Methods Mol Biol. 2017:1489:1-8. doi: 10.1007/978-1-4939-6430-7_1.

Author

Masaharu Takigawa¹

Affiliation

¹ Advanced Research Center for Oral and Craniofacial Sciences, Okayama University Dental School/Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1, Shikata-cho, Kita-ku, Okayama, 700-8525, Japan. takigawa@md.okayama-u.ac.jp.

PMID: 27734360
DOI: 10.1007/978-1-4939-6430-7_1

Abstract

I introduce the general structures and functions of CCN proteins and possible molecular mechanisms regarding the unique biological actions of this new family of signaling regulators, which may be referred to as "signal conductors." Relevance to pathology is also briefly introduced. The information provided in this overview should be useful for readers of the following chapters.

Keywords: CCN family; Matricellular protein; Signal conductor; Signaling; Structure.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Animals
CCN Intercellular Signaling Proteins / chemistry
CCN Intercellular Signaling Proteins / genetics*
CCN Intercellular Signaling Proteins / metabolism*
Carrier Proteins
Disease Susceptibility
Gene Expression Regulation
Genetic Loci
Humans
Multigene Family
Protein Binding
Signal Transduction
Structure-Activity Relationship

Substances

CCN Intercellular Signaling Proteins
Carrier Proteins