Progress on the autophagic regulators and receptors in plants

Yi Chuan. 2016 Jul 20;38(7):644-650. doi: 10.16288/j.yczz.15-525.

Abstract

Autophagy is an evolutionarily highly conserved catabolic pathway among eukaryotic cells that protects the organisms against environmental stress. Normally, autophagy is mainly involved with autophagy-related proteins(ATGs) and autophagic regulators including a series of cytoplasmic proteins and small molecules. Besides, the selective autophagy, which targets damaged organalles or protein aggregates, is mediated by the additional receptors to help the ATGs recognize different substrates. In this review, we summarize recent advances in autophagic regulators like ROS(Reactive oxygen species), TOR(Target of rapamycin) and receptors like NBR1(Neighbor of BRCA1 gene protein), RPN10(Regulatory particle non-ATPase 10) as well as their functional mechanisms mainly in Arabidopsis thaliana.

Publication types

  • Review

MeSH terms

  • Arabidopsis Proteins / physiology
  • Autophagy*
  • Carrier Proteins / physiology
  • Humans
  • Intracellular Signaling Peptides and Proteins
  • Plant Proteins / physiology*
  • Proteins / physiology
  • TOR Serine-Threonine Kinases / physiology
  • Vesicular Transport Proteins / physiology

Substances

  • ATI1 protein, Arabidopsis
  • Arabidopsis Proteins
  • Carrier Proteins
  • Intracellular Signaling Peptides and Proteins
  • NBR1 protein, Arabidopsis
  • OSTF1 protein, human
  • Plant Proteins
  • Proteins
  • RPN10 protein, Arabidopsis
  • Vesicular Transport Proteins
  • TOR Serine-Threonine Kinases