Metformin Activates AMPK through the Lysosomal Pathway

Cell Metab. 2016 Oct 11;24(4):521-522. doi: 10.1016/j.cmet.2016.09.003.

Authors

Chen-Song Zhang¹, Mengqi Li¹, Teng Ma¹, Yue Zong¹, Jiwen Cui¹, Jin-Wei Feng¹, Yu-Qing Wu¹, Shu-Yong Lin¹, Sheng-Cai Lin²

Affiliations

¹ State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, Fujian 361102, China.
² State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, Fujian 361102, China. Electronic address: linsc@xmu.edu.cn.

PMID: 27732831
DOI: 10.1016/j.cmet.2016.09.003

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

AMP-Activated Protein Kinases / metabolism*
Animals
Diabetes Mellitus, Type 2 / drug therapy
Diabetes Mellitus, Type 2 / metabolism
Enzyme Activation / drug effects*
Hepatocytes / drug effects
Hepatocytes / metabolism
Humans
Hypoglycemic Agents / pharmacology*
Lysosomes / drug effects*
Lysosomes / metabolism
Metformin / pharmacology*
Signal Transduction / drug effects*

Substances

Hypoglycemic Agents
Metformin
AMP-Activated Protein Kinases