What we need to know when performing and interpreting US elastography

Clin Mol Hepatol. 2016 Sep;22(3):406-414. doi: 10.3350/cmh.2016.0106.

Abstract

According to the increasing need for accurate staging of hepatic fibrosis, the ultrasound (US) elastography techniques have evolved significantly over the past two decades. Currently, US elastography is increasingly used in clinical practice. Previously published studies have demonstrated the excellent diagnostic performance of US elastography for the detection and staging of liver fibrosis. Although US elastography may seem easy to perform and interpret, there are many technical and clinical factors which can affect the results of US elastography. Therefore, clinicians who are involved with US elastography should be aware of these factors. The purpose of this article is to present a brief overview of US techniques with the relevant technology, the clinical indications, diagnostic performance, and technical and biological factors which should be considered in order to avoid misinterpretation of US elastography results.

Keywords: Liver fibrosis, Liver stiffness; Shear wave elastography; Transient elastography; Ultrasound elastography.

MeSH terms

  • Disease Progression
  • Elasticity Imaging Techniques / instrumentation
  • Elasticity Imaging Techniques / methods*
  • Fatty Liver / complications
  • Fatty Liver / diagnostic imaging
  • Humans
  • Hypertension, Portal / complications
  • Liver / diagnostic imaging*
  • Liver / physiopathology
  • Liver Cirrhosis / diagnostic imaging
  • Liver Cirrhosis / pathology