Rapid and safe ASAP acquisition with EXACT NMR

I E Ndukwe; A Shchukina; K Kazimierczuk; C P Butts

doi:10.1039/c6cc07140f

Rapid and safe ASAP acquisition with EXACT NMR

Chem Commun (Camb). 2016 Oct 20;52(86):12769-12772. doi: 10.1039/c6cc07140f.

Authors

I E Ndukwe¹, A Shchukina², K Kazimierczuk³, C P Butts¹

Affiliations

¹ School of Chemistry, University of Bristol, Cantocks Close, Bristol, BS8 1TS, UK. Craig.Butts@bris.ac.uk.
² Centre of New Technologies, University of Warsaw, Banacha 2C, 02089, Warszawa, Poland and Institute for Spectroscopy, Russian Academy of Sciences, Fizicheskaya 5, 142190, Moscow, Troitsk, Russia.
³ Centre of New Technologies, University of Warsaw, Banacha 2C, 02089, Warszawa, Poland.

PMID: 27727337
DOI: 10.1039/c6cc07140f

Abstract

The dangerously high power levels required for fast ASAP-HSQC and ASAP-HMQC experiments are mitigated by employing EXACT NMR. The utility of this technique is demonstrated by application of the EXACT ASAP-HSQC to chemical reaction monitoring, accelerating data acquisition by up to 2 orders of magnitude - providing evidence of it's value in fast quantitative NMR processes.