Molecular epidemiology of coxsackievirus A16 strains from four sentinel surveillance sites in Peru

Int J Infect Dis. 2016 Nov:52:83-85. doi: 10.1016/j.ijid.2016.10.003. Epub 2016 Oct 6.

Abstract

Objectives: To determine the molecular epidemiology of seven coxsackievirus A16 (CVA16) strains previously reported by this research group.

Methods: Full-length VP1 and VP4 sequences were obtained and phylogenetic analyses were performed.

Results: Six strains were classified as genotype C. Moreover, one divergent strain not clustered in any of the three currently reported genotypes was found.

Conclusion: This is the first report of CVA16 in Peru and provides valuable baseline data about its potential distribution in South America, as well as evidence of a potential divergent genotype that has never before been reported.

Keywords: Coxsackievirus A16; Enterovirus; Peru.

MeSH terms

  • Child
  • Child, Preschool
  • Coxsackievirus Infections / epidemiology
  • Coxsackievirus Infections / virology*
  • Enterovirus / classification*
  • Enterovirus / isolation & purification
  • Enterovirus A, Human / classification
  • Female
  • Genotype
  • Humans
  • Infant
  • Male
  • Molecular Epidemiology
  • Molecular Sequence Data
  • Peru
  • Phylogeny
  • Sentinel Surveillance
  • South America