Palatal botulinum toxin as a novel therapy for objective tinnitus in forced eyelid closure syndrome

Laryngoscope. 2017 May;127(5):1199-1201. doi: 10.1002/lary.26191. Epub 2016 Sep 26.

Abstract

Objective tinnitus associated with eyelid closure is a rare clinical entity with only a few reported cases. This association previously was identified as forced eyelid closure syndrome (FECS) and involves an aberrant neural reflex between cranial nerve VII (activating the orbicularis oculi muscle) and cranial nerve V (activating the tensor tympani muscle). We present a 52-year-old Caucasian female with a 2-month history of FECS who was successfully treated with intrapalatal botulinum toxin, with full resolution of her objective tinnitus symptoms. This is the first reported use of botulinum toxin in FECS. Laryngoscope, 127:1199-1201, 2017.

Keywords: FECS; botulinum toxin; objective tinnitus; palatal tinnitus.

Publication types

  • Case Reports

MeSH terms

  • Botulinum Toxins, Type A / therapeutic use*
  • Eyelids / physiopathology
  • Facial Nerve / physiopathology
  • Female
  • Humans
  • Middle Aged
  • Neuromuscular Agents / therapeutic use*
  • Palate
  • Syndrome
  • Tinnitus / drug therapy*
  • Tinnitus / physiopathology
  • Trigeminal Nerve / physiopathology

Substances

  • Neuromuscular Agents
  • Botulinum Toxins, Type A