Utilization of next generation sequencing identifies potentially actionable mutations in chronic lymphocytic leukaemia

Br J Haematol. 2018 Jan;180(2):299-301. doi: 10.1111/bjh.14315. Epub 2016 Oct 7.

Authors

Jie Wang¹, Jennifer Morrissette², David B Lieberman², Colleen Timlin¹, Stephen J Schuster¹, Anthony R Mato¹

Affiliations

¹ Center for CLL, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA.
² Center for Personalized Diagnostics, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA.

PMID: 27714764
DOI: 10.1111/bjh.14315

No abstract available

Keywords: chronic lymphocytic leukaemia; mutation analysis; mutation detection.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Biomarkers, Tumor
Genetic Association Studies
Genetic Predisposition to Disease
Genomics / methods
High-Throughput Nucleotide Sequencing*
Humans
Leukemia, Lymphocytic, Chronic, B-Cell / genetics*
Leukemia, Lymphocytic, Chronic, B-Cell / metabolism
Mutation*
Oncogenes*

Substances

Biomarkers, Tumor