Toward Self-Powered Wearable Adhesive Skin Patch with Bendable Microneedle Array for Transdermal Drug Delivery

Hao Wang; Giorgia Pastorin; Chengkuo Lee

doi:10.1002/advs.201500441

Toward Self-Powered Wearable Adhesive Skin Patch with Bendable Microneedle Array for Transdermal Drug Delivery

Adv Sci (Weinh). 2016 Apr 19;3(9):1500441. doi: 10.1002/advs.201500441. eCollection 2016 Sep.

Authors

Hao Wang¹, Giorgia Pastorin², Chengkuo Lee¹

Affiliations

¹ Department of Electrical and Computer EngineeringNational University of Singapore4 Engineering Drive 3Singapore117576Singapore; Center for Sensors and MEMSNational University of Singapore4 Engineering Drive 3Singapore117576Singapore; Singapore Institute for Neurotechnology (SiNAPSE)National University of Singapore28 Medical Drive, #05-CORSingapore117456Singapore; NUS Suzhou Research Institute (NUSRI)Suzhou Industrial ParkSuzhou215123P. R. China.
² Pharmacy Department National University of SingaporeSingapore117543Singapore; NanoCoreFaculty of EngineeringNational University of SingaporeSingapore117576Singapore; NUS Graduate School for Integrative Sciences and EngineeringCentre for Life Sciences (CeLS)Singapore117456Singapore.

Abstract

A wearable adhesive skin patch for transdermal drug delivery is developed with bendable microneedles, dry adhesive and triboelectric energy harvester (TEH). The bendable microneedle array can overcome the needle breakage issue. The dry adhesive can realize a conformal attachment. The TEH can generate power when attached on flat skin or joint to power active components to be integrated in the future.

Keywords: bendable microneedle; self‐powered; wearable adhesive skin patch.