Densely Packed Microgoblet Laser Pairs for Cross-Referenced Biomolecular Detection

Adv Sci (Weinh). 2015 Jun 8;2(10):1500066. doi: 10.1002/advs.201500066. eCollection 2015 Oct.

Abstract

Microgoblet laser pairs are presented for cross-referenced on-chip biomolecular sensing. Parallel readout of the micro-lasers facilitates effective mutual filtering of highly localized refractive index and temperature fluctuations in the analyte. Cross-referenced detection of two different types of proteins and complete chemical transducer reconfiguration is demonstrated. Selective surface functionalization of the individual lasers with high spatial accuracy is achieved by aligned microcontact stamping.

Keywords: aligned microcontact stamping; biosensing; microlasers; multiplexed surface functionalization; whispering gallery mode resonators.