Future therapeutic potential of SAP-1 in inflammatory bowel diseases

Expert Rev Gastroenterol Hepatol. 2016 Dec;10(12):1313-1315. doi: 10.1080/17474124.2016.1245144. Epub 2016 Oct 19.
No abstract available

Keywords: CEACAM20; Protein tyrosine phosphatase; SAP-1; inflammatory bowel diseases; interleukin-10; intestinal epithelial cells; tyrosine phosphorylation.

Publication types

  • Editorial

MeSH terms

  • Animals
  • Cell Adhesion Molecules / metabolism
  • Epithelial Cells / drug effects*
  • Epithelial Cells / enzymology
  • Epithelial Cells / immunology
  • Gastrointestinal Agents / therapeutic use*
  • Humans
  • Immunity, Mucosal / drug effects*
  • Inflammatory Bowel Diseases / drug therapy*
  • Inflammatory Bowel Diseases / enzymology
  • Inflammatory Bowel Diseases / immunology
  • Intestinal Mucosa / drug effects*
  • Intestinal Mucosa / enzymology
  • Intestinal Mucosa / immunology
  • Molecular Targeted Therapy
  • Phosphorylation
  • Receptor-Like Protein Tyrosine Phosphatases, Class 3 / metabolism
  • Receptor-Like Protein Tyrosine Phosphatases, Class 3 / therapeutic use*
  • Signal Transduction / drug effects
  • Tyrosine

Substances

  • CEACAM20 protein, human
  • Cell Adhesion Molecules
  • Gastrointestinal Agents
  • Tyrosine
  • Receptor-Like Protein Tyrosine Phosphatases, Class 3