Intestinal Failure in Children

Indian J Pediatr. 2016 Nov;83(12-13):1436-1443. doi: 10.1007/s12098-016-2219-7. Epub 2016 Oct 5.

Abstract

Children with intestinal failure have had improved survival, particularly those with extreme short bowel syndrome, over the last 10-15 y. This has been attributed to better understanding of the pathophysiology of intestinal failure, improvement in line care, recognition of the importance of a team approach as well as the progress of intestinal transplant as a viable option. Parenteral nutrition remains the cornerstone for the continual survival of these patients. This review will cover contemporary approaches to intestinal failure including post surgical approaches, non-transplant surgery, dietetic and medication approaches during the adaptation process, considerations for home parenteral nutrition and latest in intestinal transplantation.

Keywords: Faltering growth; Growth; Intestinal failure; Intestinal transplantation; Parenteral nutrition; STEP procedure; Total parenteral nutrition.

Publication types

  • Review

MeSH terms

  • Child
  • Humans
  • Intestines
  • Parenteral Nutrition
  • Parenteral Nutrition, Total
  • Short Bowel Syndrome / physiopathology*
  • Short Bowel Syndrome / therapy