The metabolome 18 years on: a concept comes of age

Douglas B Kell; Stephen G Oliver

doi:10.1007/s11306-016-1108-4

The metabolome 18 years on: a concept comes of age

Metabolomics. 2016;12(9):148. doi: 10.1007/s11306-016-1108-4. Epub 2016 Sep 2.

Authors

Douglas B Kell¹, Stephen G Oliver²

Affiliations

¹ School of Chemistry, The University of Manchester, 131 Princess St, Manchester, M1 7DN UK ; Manchester Institute of Biotechnology, The University of Manchester, 131 Princess St, Manchester, M1 7DN UK ; Centre for Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM), The University of Manchester, 131, Princess St, Manchester, M1 7DN UK.
² Cambridge Systems Biology Centre, University of Cambridge, Sanger Building, 80 Tennis Court Road, Cambridge, CB2 1GA UK ; Department of Biochemistry, University of Cambridge, Sanger Building, 80 Tennis Court Road, Cambridge, CB2 1GA UK.

Abstract

Background: The term 'metabolome' was introduced to the scientific literature in September 1998.

Aim and key scientific concepts of the review: To mark its 18-year-old 'coming of age', two of the co-authors of that paper review the genesis of metabolomics, whence it has come and where it may be going.

Keywords: Functional genomics; Metabolome; Precision medicine; Systems biology.

Publication types

Review