The higher prevalence of missense mutations in hemophilia B compared to hemophilia A could be important in determining a milder clinical phenotype in patients with severe hemophilia B
1 Department of Experimental and Clinical Medicine, Section of Internal Medicine, University of Florence, Rheumatology Unit, Careggi University Hospital, Florence, Italy daniela.melchiorre@unifi.it.
2 Center for Bleeding Disorders, Careggi University Hospital, Florence, Italy.