Bypass graft infection and bacteremia caused by Anaerostipes caccae: First report of human infection caused by a recently described gut anaerobe

Meklit Workneh; Frances Wang; Mark Romagnoli; Patricia J Simner; Karen Carroll

doi:10.1016/j.anaerobe.2016.09.005

Bypass graft infection and bacteremia caused by Anaerostipes caccae: First report of human infection caused by a recently described gut anaerobe

Anaerobe. 2016 Dec:42:98-100. doi: 10.1016/j.anaerobe.2016.09.005. Epub 2016 Sep 28.

Authors

Meklit Workneh¹, Frances Wang², Mark Romagnoli³, Patricia J Simner⁴, Karen Carroll⁴

Affiliations

¹ Division of Infectious Diseases, Department of Internal Medicine, Johns Hopkins School of Medicine, 1830 East Monument Street, Room 448, Baltimore, MD 21287, USA. Electronic address: mworkne1@jhmi.edu.
² Johns Hopkins School of Medicine, Baltimore, MD, USA.
³ Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
⁴ Johns Hopkins Medical Institutions, Department of Pathology, Division of Medical Microbiology, Baltimore, MD, USA.

PMID: 27693544
DOI: 10.1016/j.anaerobe.2016.09.005

Abstract

We report a case of bypass graft infection and bacteremia caused by Anaerostipes caccae. A review of the literature shows no reported human infection caused by this microorganism to date. The patient was initially treated with vancomycin and piperacillin-tazobactam on admission and with amoxicillin-clavulanate upon discharge. The slow-growing organism was subsequently found to be susceptible to metronidazole and ertapenem.

Keywords: 16S rRNA; Anaerostipes caccae; Bacteremia; Bypass graft infection.

Publication types

Case Reports

MeSH terms

Adult
Amoxicillin-Potassium Clavulanate Combination / therapeutic use
Anastomosis, Surgical / methods
Anti-Bacterial Agents / therapeutic use*
Blood Culture
Clostridiales / drug effects
Clostridiales / growth & development
Clostridiales / isolation & purification*
Ertapenem
Female
Gram-Positive Bacterial Infections / diagnosis*
Gram-Positive Bacterial Infections / drug therapy
Gram-Positive Bacterial Infections / microbiology
Gram-Positive Bacterial Infections / pathology
Humans
Metronidazole / therapeutic use
Penicillanic Acid / analogs & derivatives
Penicillanic Acid / therapeutic use
Piperacillin / therapeutic use
Piperacillin, Tazobactam Drug Combination
Surgical Wound Infection / diagnosis*
Surgical Wound Infection / drug therapy
Surgical Wound Infection / microbiology
Surgical Wound Infection / pathology
Vancomycin / therapeutic use
beta-Lactams / therapeutic use

Substances

Anti-Bacterial Agents
beta-Lactams
Metronidazole
Piperacillin, Tazobactam Drug Combination
Vancomycin
Amoxicillin-Potassium Clavulanate Combination
Penicillanic Acid
Ertapenem
Piperacillin