Cardiotoxicity of nano-particles

Life Sci. 2016 Nov 15:165:91-99. doi: 10.1016/j.lfs.2016.09.017. Epub 2016 Sep 26.

Abstract

Nano-particles (NPs) are used in industrial and biomedical fields such as cosmetics, food additives and biosensors. Beside their favorable properties, nanoparticles are responsible for toxic effects. Local adverse effects and/or systemic toxicity are described with nanoparticle delivery to target organs of the human body. Animal studies provide evidence for the aforementioned toxicity. Cardiac function is a specific target of nanoparticles. Thus, reviewing the current bibliography on cardiotoxicity of nanoparticles and specifically of titanium, zinc, silver, carbon, silica and iron oxide nano-materials is the aim of this study.

Keywords: Cardiac toxicity; Inflammatory marker; Nano-particle; Reactive oxygen species.

Publication types

  • Review

MeSH terms

  • Heart / drug effects*
  • Humans
  • Nanoparticles / toxicity*