Marine copepod cytochrome P450 genes and their applications for molecular ecotoxicological studies in response to oil pollution

Mar Pollut Bull. 2017 Nov 30;124(2):953-961. doi: 10.1016/j.marpolbul.2016.09.048. Epub 2016 Sep 28.

Abstract

Recently, accidental spills of heavy oil have caused adverse effects in marine organisms. Oil pollution can induce damages on development and reproduction, linking with detrimental effects on diverse molecular levels of genes and proteins in plankton and fish. However, most information was mainly focused on marine vertebrates and consequently, limited information was available in marine invertebrates. Furthermore, there is still a lack of knowledge bridging in vivo endpoints with the functional regulation of cytochrome P450 (CYP) genes in response to oil spill pollution in marine invertebrates. In this paper, adverse effects of oil spill pollution in marine invertebrates are summarized with the importance of CYP genes as a potential biomarker, applying for environmental monitoring to detect oil spill using marine copepods.

Keywords: Cytochrome P450 (CYP); Paracyclopina nana; Tigriopus japonicus; Water accommodated fraction (WAF); copepod.

MeSH terms

  • Animals
  • Arthropod Proteins / genetics*
  • Arthropod Proteins / metabolism
  • Copepoda / drug effects*
  • Copepoda / genetics
  • Copepoda / metabolism
  • Cytochrome P-450 Enzyme System / genetics*
  • Cytochrome P-450 Enzyme System / metabolism
  • Ecotoxicology / methods*
  • Environmental Exposure*
  • Environmental Monitoring / methods*
  • Petroleum Pollution / adverse effects*

Substances

  • Arthropod Proteins
  • Cytochrome P-450 Enzyme System