1 MRC Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, UK.
2 The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
3 MRC Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, UK; The UCL Cancer Institute, University College London, London WC1E 6BT, UK. Electronic address: r.debruin@ucl.ac.uk.
Styles et al. develop an optimized method that combines high-content microscopy and automated phenotypic analysis with genome-wide yeast genetics to identify genes in DNA damage repair.