Silk patterns made by direct femtosecond laser writing

Biomicrofluidics. 2016 Sep 2;10(5):054101. doi: 10.1063/1.4962294. eCollection 2016 Sep.

Abstract

Silk patterns in a film of amorphous water-soluble fibroin are created by tailored exposure to femtosecond-laser pulses (1030 nm/230 fs) without the use of photo-initiators. This shows that amorphous silk can be used as a negative tone photo-resist. It is also shown that water insoluble crystalline silk films can be precisely ablated from a glass substrate achieving the patterns of crystalline silk gratings on a glass substrate. Bio-compatible/degradable silk can be laser structured to achieve conformational transformations as demonstrated by infrared spectroscopy.