History of schistosomiasis epidemiology, current status, and challenges in China: on the road to schistosomiasis elimination

Parasitol Res. 2016 Nov;115(11):4071-4081. doi: 10.1007/s00436-016-5253-5. Epub 2016 Sep 28.

Abstract

Schistosomiasis is a snail-borne disease caused by worms of the genus Schistosoma. Worldwide, human schistosomiasis remains a serious public health problem, threatening ∼800 million people in 78 countries with a loss of 70 million disability-adjusted life years. Schistosoma japonicum is the only human blood fluke that occurs in China. As one of the countries suffering greatly from schistosomiasis, over the past 65 years, China has made great strides in controlling schistosomiasis, blocking the transmission of S. japonicum in five provinces, remarkably reducing transmission intensities in the other seven endemic provinces, and China is currently preparing to move toward the elimination of this disease before 2025. However, while on the road to schistosomiasis elimination, emerging challenges merit attention, including severe advanced cases, increased movements of population and livestock, large-area distribution of intermediate host snails, limitations of new drug developments and no vaccine available, as well as imported schistosomiasis and its potential risk.

Keywords: Elimination of schistosomiasis; Emerging challenges; P. R. China; Schistosoma japonicum.

Publication types

  • Review

MeSH terms

  • Animals
  • China / epidemiology
  • Disease Eradication
  • Disease Vectors*
  • Humans
  • Livestock
  • Public Health
  • Schistosoma japonicum / physiology*
  • Schistosomiasis / epidemiology*
  • Schistosomiasis / prevention & control
  • Schistosomiasis / transmission
  • Schistosomiasis japonica / epidemiology
  • Schistosomiasis japonica / prevention & control
  • Schistosomiasis japonica / transmission
  • Snails / parasitology*