New quality assurance program integrating "modern radiotherapy" within the German Hodgkin Study Group

Strahlenther Onkol. 2017 Feb;193(2):100-108. doi: 10.1007/s00066-016-1048-y. Epub 2016 Sep 27.

Abstract

Introduction: Field design changed substantially from extended-field RT (EF-RT) to involved-field RT (IF-RT) and now to involved-node RT (IN-RT) and involved-site RT (IS-RT) as well as treatment techniques in radiotherapy (RT) of Hodgkin's lymphoma (HL). The purpose of this article is to demonstrate the establishment of a quality assurance program (QAP) including modern RT techniques and field designs within the German Hodgkin Study Group (GHSG).

Methods: In the era of modern conformal RT, this QAP had to be fundamentally adapted and a new evaluation process has been intensively discussed by the radiotherapeutic expert panel of the GHSG.

Results: The expert panel developed guidelines and criteria to analyse "modern" field designs and treatment techniques. This work is based on a dataset of 11 patients treated within the sixth study generation (HD16-17).

Conclusion: To develop a QAP of "modern RT", the expert panel defined criteria for analysing current RT procedures. The consensus of a modified QAP in ongoing and future trials is presented. With this schedule, the QAP of the GHSG could serve as a model for other study groups.

Keywords: Intensity-modulated radiotherapy; Lymphoma; Organs at risk; Sequelae; Treatment failure.

Publication types

  • Clinical Trial

MeSH terms

  • Germany / epidemiology
  • Guideline Adherence / standards
  • Guideline Adherence / statistics & numerical data*
  • Hodgkin Disease / epidemiology*
  • Hodgkin Disease / radiotherapy*
  • Humans
  • Practice Guidelines as Topic*
  • Prevalence
  • Quality Assurance, Health Care / statistics & numerical data*
  • Radiation Oncology / standards*
  • Radiotherapy, Conformal / standards*
  • Radiotherapy, Conformal / statistics & numerical data
  • Risk Factors
  • Systems Integration
  • Treatment Outcome