Assessment of the extent of microcalcifications to predict the size of a ductal carcinoma in situ: comparison between tomosynthesis and conventional mammography

Clin Imaging. 2016 Nov-Dec;40(6):1269-1273. doi: 10.1016/j.clinimag.2016.09.003. Epub 2016 Sep 13.

Abstract

Objectives: The objective was to determine if digital tomosynthesis of the breast (DBT) assesses the extension of ductal carcinoma in situ (DCIS) with higher precision than mammography (MG).

Material and methods: The local ethics committee approved this retrospective study including 26 patients with DCIS, which were rated by three radiologists. Statistics were performed using intraclass correlation (ICC) for interreader agreement and the Pearson correlation for correlation of MG and DBT. Standard of reference was the histologic extension.

Results: The ICC was excellent. Correlation between MG and histology was 0.879 (P<.01) and for DBT and histology was 0.914 (P<.01).

Conclusion: DBT provides a slightly better estimation of the size of a DCIS than MG.

Keywords: Breast; DCIS; Mammography; Microcalcification; Tomosynthesis.

MeSH terms

  • Aged
  • Breast Neoplasms / diagnostic imaging*
  • Breast Neoplasms / pathology*
  • Calcinosis / diagnostic imaging*
  • Carcinoma, Intraductal, Noninfiltrating / diagnostic imaging*
  • Carcinoma, Intraductal, Noninfiltrating / pathology*
  • Female
  • Humans
  • Imaging, Three-Dimensional*
  • Mammography / methods*
  • Middle Aged
  • Retrospective Studies