[Well's cellulitis: A case report]

Rev Med Interne. 2017 Jun;38(6):407-411. doi: 10.1016/j.revmed.2016.08.022. Epub 2016 Sep 23.
[Article in French]

Abstract

Introduction: Wells's cellulitis is a rare eosinophilic dermatose characterized by an inflammatory erythematous eruption, often associated with eosinophilia, and suggestive histologic features. The differential diagnosis with other eosinophilic dermatitis is problematic. The treatment is typically based on systemic steroids.

Case report: We report a 63-year-old patient with an extensive pruritic maculo-papular eruption of the limbs and the trunk, forming large indurated and painful erythematous patches. Blood analysis revealed eosinophilia. Histologic examination showed perivascular eosinophilic inflammatory infiltration, also disposed around collagen fibers. The symptoms disappeared with topical corticosteroids.

Conclusion: The diagnosis of Well's cellulitis is difficult because of the lack of specific sign; it is based on suggestive clinical, biological and histological features. Topical corticosteroids are efficient and well-tolerated, and should be used as first treatment.

Keywords: Cellulite de Wells; Dermatose éosinophilique; Eosinophilia; Eosinophilic dermatoses; Hyperéosinophilie; Well's cellulitis.

Publication types

  • Case Reports

MeSH terms

  • Cellulitis / diagnosis*
  • Cellulitis / drug therapy
  • Diagnosis, Differential
  • Eosinophilia / diagnosis*
  • Eosinophilia / drug therapy
  • Female
  • Glucocorticoids / therapeutic use
  • Humans
  • Middle Aged

Substances

  • Glucocorticoids

Supplementary concepts

  • Wells syndrome