Exercise increases the level of plasma orexin A in humans

J Basic Clin Physiol Pharmacol. 2016 Nov 1;27(6):611-616. doi: 10.1515/jbcpp-2015-0133.

Abstract

Background: The purpose of this research was to study the effects of exercise on the concentration of plasma orexin A, a peptide regulating several physiological functions.

Methods: Blood samples were collected from participants (men, n=10; age: 24.4±2.93 years) 15, 0 min before the start of exercise, and 30, 45, 60 min after a cycle ergometer exercise at 75 W for 15 min. Also heart rate (HR), galvanic skin response (GSR), and rectal temperature were monitored.

Results: The exercise induced a significant increase (p<0.01) in plasmatic orexin A with a peak at 30 min after the exercise bout, in association with an increase of the other three monitored variables: HR (p<0.01), GSR (p<0.05), and rectal temperature (p<0.01).

Conclusions: Our findings indicate that plasmatic orexin A is involved in the reaction to physical activity.

MeSH terms

  • Adult
  • Biomarkers / blood
  • Body Temperature / physiology
  • Exercise / physiology*
  • Exercise Test / methods
  • Fever / blood
  • Heart Rate / physiology
  • Humans
  • Male
  • Orexins / blood*
  • Young Adult

Substances

  • Biomarkers
  • Orexins