Multidrug-Resistant Pseudomonas aeruginosa Infection in a Child with Cystic Fibrosis

Antimicrob Agents Chemother. 2016 Sep 23;60(10):5627-30. doi: 10.1128/AAC.00705-16. Print 2016 Oct.

Abstract

We describe a pediatric cystic fibrosis patient who developed a pulmonary exacerbation due to two multidrug-resistant (MDR) Pseudomonas aeruginosa isolates. In addition to these MDR organisms, the case was further complicated by β-lactam allergy. Despite the MDR phenotype, both isolates were susceptible to an antimicrobial combination.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Amikacin / therapeutic use
  • Anti-Bacterial Agents / adverse effects
  • Anti-Bacterial Agents / therapeutic use*
  • Ciprofloxacin / therapeutic use
  • Cystic Fibrosis / complications*
  • Cystic Fibrosis / microbiology
  • Drug Hypersensitivity / etiology
  • Drug Resistance, Multiple, Bacterial / drug effects*
  • Drug Therapy, Combination
  • Female
  • Humans
  • Microbial Sensitivity Tests
  • Penicillanic Acid / analogs & derivatives
  • Penicillanic Acid / therapeutic use
  • Pseudomonas Infections / drug therapy*
  • Pseudomonas Infections / microbiology
  • Pseudomonas aeruginosa / drug effects*
  • Pseudomonas aeruginosa / pathogenicity
  • Tazobactam
  • beta-Lactams / adverse effects

Substances

  • Anti-Bacterial Agents
  • beta-Lactams
  • Ciprofloxacin
  • Amikacin
  • Penicillanic Acid
  • Tazobactam