Complete Genome Sequence of Streptomyces clavuligerus F613-1, an Industrial Producer of Clavulanic Acid

Guangxiang Cao; Chuanqing Zhong; Gongli Zong; Jiafang Fu; Zhong Liu; Guimin Zhang; Ronghuo Qin

doi:10.1128/genomeA.01020-16

Complete Genome Sequence of Streptomyces clavuligerus F613-1, an Industrial Producer of Clavulanic Acid

Genome Announc. 2016 Sep 22;4(5):e01020-16. doi: 10.1128/genomeA.01020-16.

Authors

Guangxiang Cao¹, Chuanqing Zhong², Gongli Zong³, Jiafang Fu³, Zhong Liu⁴, Guimin Zhang⁴, Ronghuo Qin³

Affiliations

¹ Shandong Medicinal Biotechnology Centre, Shandong Academy of Medical Sciences, Jinan, China National Engineering Research Center of Chiral Drugs, Lunan Pharmaceutical Group Corporation, Linyi, China caozhong0402@163.com.
² Shandong Jianzhu University, Jinan, China.
³ Shandong Medicinal Biotechnology Centre, Shandong Academy of Medical Sciences, Jinan, China.
⁴ National Engineering Research Center of Chiral Drugs, Lunan Pharmaceutical Group Corporation, Linyi, China.

Abstract

Streptomyces clavuligerus strain F613-1 is an industrial strain with high-yield clavulanic acid production. In this study, the complete genome sequence of S. clavuligerus strain F613-1 was determined, including one linear chromosome and one linear plasmid, carrying numerous sets of genes involving in the biosynthesis of clavulanic acid.