High-dose cytarabine added to CY/TBI improves the prognosis of cord blood transplantation for acute lymphoblastic leukemia in adults: a retrospective cohort study

Y Arai; T Kondo; A Shigematsu; J Tanaka; S Takahashi; T Kobayashi; N Uchida; Y Onishi; J Ishikawa; H Kanamori; M Sawa; A Yokota; Y Kouzai; M Takanashi; T Ichinohe; Y Atsuta; S Mizuta

doi:10.1038/bmt.2016.242

High-dose cytarabine added to CY/TBI improves the prognosis of cord blood transplantation for acute lymphoblastic leukemia in adults: a retrospective cohort study

Bone Marrow Transplant. 2016 Dec;51(12):1636-1639. doi: 10.1038/bmt.2016.242. Epub 2016 Sep 19.

Authors

Y Arai¹, T Kondo¹, A Shigematsu², J Tanaka³, S Takahashi⁴, T Kobayashi⁵, N Uchida⁶, Y Onishi⁷, J Ishikawa⁸, H Kanamori⁹, M Sawa¹⁰, A Yokota¹¹, Y Kouzai¹², M Takanashi¹³, T Ichinohe¹⁴, Y Atsuta^{15

16}, S Mizuta¹⁷

Affiliations

¹ Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
² Department of Hematology, Sapporo Hokuyu Hospital, Sapporo, Japan.
³ Department of Hematology, Tokyo Women's Medical University, Tokyo, Japan.
⁴ Division of Molecular Therapy, The Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
⁵ Division of Hematology, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan.
⁶ Department of Hematology, Federation of National Public Service Personnel Mutual Aid Associations Toranomon Hospital, Tokyo, Japan.
⁷ Department of Hematology and Rheumatology, Tohoku University Hospital, Sendai, Japan.
⁸ Department of Hematology and Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan.
⁹ Department of Hematology, Kanagawa Cancer Center, Yokohama, Japan.
¹⁰ Department of Hematology and Oncology, Anjo Kosei Hospital, Anjo, Japan.
¹¹ Department of Hematology, Chiba Aoba Municipal Hospital, Chiba, Japan.
¹² Department of Transfusion Medicine, Tokyo Metropolitan Tama Medical Center, Fuchu, Japan.
¹³ Blood Service Headquarters, Japanese Red Cross Society, Tokyo, Japan.
¹⁴ Department of Hematology and Oncology, Hiroshima University Hospital, Hiroshima, Japan.
¹⁵ Japanese Data Center for Hematopoietic Cell Transplantation, Nagoya, Japan.
¹⁶ Department of Healthcare Administration, Nagoya University Graduate School of Medicine, Nagoya, Japan.
¹⁷ Division of Hematology, Fujita Health University, Toyoake, Japan.

PMID: 27643870
DOI: 10.1038/bmt.2016.242

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Bone Marrow Transplantation
Cord Blood Stem Cell Transplantation*
Cyclophosphamide / therapeutic use
Cytarabine / therapeutic use*
Female
Fetal Blood
Humans
Kaplan-Meier Estimate
Male
Middle Aged
Peripheral Blood Stem Cell Transplantation*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy*
Prognosis
Proportional Hazards Models
Recurrence
Retrospective Studies
Transplantation Conditioning*
Treatment Outcome
Whole-Body Irradiation
Young Adult

Substances

Cytarabine
Cyclophosphamide