Heterogeneous inflammatory patterns in chronic rhinosinusitis without nasal polyps in Chicago, Illinois

Bruce K Tan; Aiko I Klingler; Julie A Poposki; Whitney W Stevens; Anju T Peters; Lydia A Suh; James Norton; Roderick G Carter; Kathryn E Hulse; Kathleen E Harris; Leslie C Grammer; Robert P Schleimer; Kevin C Welch; Stephanie S Smith; David B Conley; Robert C Kern; Atsushi Kato

doi:10.1016/j.jaci.2016.06.063

Heterogeneous inflammatory patterns in chronic rhinosinusitis without nasal polyps in Chicago, Illinois

J Allergy Clin Immunol. 2017 Feb;139(2):699-703.e7. doi: 10.1016/j.jaci.2016.06.063. Epub 2016 Sep 14.

Authors

Bruce K Tan¹, Aiko I Klingler², Julie A Poposki², Whitney W Stevens², Anju T Peters², Lydia A Suh², James Norton², Roderick G Carter², Kathryn E Hulse², Kathleen E Harris², Leslie C Grammer², Robert P Schleimer³, Kevin C Welch¹, Stephanie S Smith¹, David B Conley¹, Robert C Kern³, Atsushi Kato⁴

Affiliations

¹ Department of Otolaryngology, Northwestern University Feinberg School of Medicine, Chicago, Ill.
² Division of Allergy-Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
³ Department of Otolaryngology, Northwestern University Feinberg School of Medicine, Chicago, Ill; Division of Allergy-Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
⁴ Department of Otolaryngology, Northwestern University Feinberg School of Medicine, Chicago, Ill; Division of Allergy-Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill. Electronic address: a-kato@northwestern.edu.

Abstract

CRSsNP is a heterogenous disease but type 2 inflammation in CRSsNP was more common than type 1 inflammation among patients in Chicago, Illinois. Distinct therapeutic strategies may be needed depending on the type of inflammation found in CRSsNP.

Publication types

Clinical Trial
Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Aged
Chicago
Chronic Disease
Female
Humans
Inflammation / diagnostic imaging
Inflammation / immunology
Inflammation / pathology
Male
Middle Aged
Nasal Polyps / complications
Nasal Polyps / diagnostic imaging
Nasal Polyps / immunology*
Nasal Polyps / pathology
Rhinitis / complications
Rhinitis / diagnostic imaging
Rhinitis / immunology*
Rhinitis / pathology
Sinusitis / complications
Sinusitis / diagnostic imaging
Sinusitis / immunology*
Sinusitis / pathology

Abstract

Publication types

MeSH terms

Grants and funding