Consensus Document of the Spanish Society of Cardiology and the Spanish Society of Internal Medicine on the diagnosis and treatment of iron deficiency in heart failure

Rev Clin Esp (Barc). 2017 Jan-Feb;217(1):35-45. doi: 10.1016/j.rce.2016.08.001. Epub 2016 Sep 14.
[Article in English, Spanish]

Abstract

Iron deficiency in patients with heart failure is a medical problem of recent particular interest. This interest has resulted from the publication of several clinical trials that demonstrated that the administration of intravenous iron to such patients improved their functional capacity and even reduced the number of hospitalisations for heart failure decompensation. However, applying the evidence from these studies in clinical practice is still controversial, both in terms of the diagnostic criteria for iron deficiency (absolute and functional) and the optimal method for iron replenishment. This article is a consensus document that integrates the recommendations of the Spanish Society of Internal Medicine and the Spanish Society of Cardiology. The article reviews the scientific evidence and proposes a diagnostic and therapeutic performance protocol for iron deficiency in heart failure.

Keywords: Anaemia; Anemia; Déficit de hierro; Heart failure; Hierro intravenoso; Insuficiencia cardiaca; Intravenous iron; Iron deficiency.