Screening for Persistent Psychopathology in 4-Year-Old Children

Pediatrics. 2016 Oct;138(4):e20151648. doi: 10.1542/peds.2015-1648. Epub 2016 Sep 16.

Abstract

Objective: To inform primary care screening and preventive intervention efforts, the authors examined the screening efficiency of the parent version of the Strengths and Difficulties Questionnaire (SDQP4-16) for persistent disorders relative to transient disorders and its capacity to distinguish between the two.

Methods: Persistence and transience in preschool-onset psychiatric disorders were identified by using data from a large population-based cohort study in Norwegian children initially assessed at age 4 and followed up at age 6 (n = 1038). Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, diagnoses at both time points were assigned by using the Preschool Age Psychiatric Assessment Interview, against which the SDQP4-16 was compared through receiver operating characteristics analysis.

Results: The screening efficiency for persistent disorders exceeded that for transient disorders with a specificity of 86.1%, a sensitivity of 79.3%, and an area under the curve value of 0.85. The SDQP4-16 was able to discriminate persistent disorders from transient disorders at an area under the curve value of 0.71. At the selected cutoff of 10, the negative predictive value was 99.6%, whereas the positive predictive value was 9.5%, partly due to the low prevalence (1.8%) of persistent disorders.

Conclusions: The SDQP4-16 is a sensitive tool for detecting persistent psychiatric disorders in young children. However, a large proportion of positive screens are nonpersistent cases, as indicated by the high false-positive rate. Thus, the clinical utility of the SDQP4-16 in primary care screening for persistent disorders is uncertain, particularly in samples in which the rate of psychiatric disorders is low.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Area Under Curve
  • Child
  • Child, Preschool
  • Cohort Studies
  • Diagnostic and Statistical Manual of Mental Disorders
  • Female
  • Humans
  • Male
  • Mass Screening / methods*
  • Neurodevelopmental Disorders / diagnosis*
  • Norway
  • Predictive Value of Tests
  • Psychopathology / methods*
  • Sensitivity and Specificity
  • Surveys and Questionnaires