The International Takotsubo Registry: Rationale, Design, Objectives, and First Results

Jelena-R Ghadri; Victoria L Cammann; Christian Templin

doi:10.1016/j.hfc.2016.06.010

The International Takotsubo Registry: Rationale, Design, Objectives, and First Results

Heart Fail Clin. 2016 Oct;12(4):597-603. doi: 10.1016/j.hfc.2016.06.010.

Authors

Jelena-R Ghadri¹, Victoria L Cammann², Christian Templin²

Affiliations

¹ Department of Cardiology, University Heart Center, University Hospital Zurich, Raemistrasse 100, Zurich 8091, Switzerland. Electronic address: Jelena-Rima.Ghadri@usz.ch.
² Department of Cardiology, University Heart Center, University Hospital Zurich, Raemistrasse 100, Zurich 8091, Switzerland.

PMID: 27638029
DOI: 10.1016/j.hfc.2016.06.010

Abstract

Takotsubo syndrome (TTS) was first described in Japan in 1990. The clinical presentation is similar to that of acute coronary syndrome (ACS). Cardiac enzymes are commonly elevated. A global initiative was launched and the InterTAK Registry was established to provide a systematic database. The major goals of the International Takotsubo Registry (InterTAK Registry) are to provide a comprehensive clinical characterization on natural history, treatment, and outcomes. We linked a biorepository to identify biomarkers for the diagnosis and prognosis and to investigate the genetic basis as well as disease-related factors. We focus on the rationale, objectives, design, and first results of the InterTAK Registry.

Keywords: Broken heart syndrome; Cardiomyopathy; Heart failure; International Takotsubo Registry; Takotsubo syndrome.

Publication types

Review

MeSH terms

International Cooperation
Japan
Prognosis
Registries
Research Design
Takotsubo Cardiomyopathy / diagnosis*
Takotsubo Cardiomyopathy / therapy*