Abstract
Ectopic parathyroid adenomas are considered the main cause of primary hyperparathyroidism. However, concurrent parathyroid and thymic pathologies are rarely diagnosed in the same patient. A 47-year-old man with history of diabetes mellitus, hypertension, and myasthenia gravis presented with persistent hypercalcemia. Laboratory investigations, computed tomography, and technetium-99 m sestamibi scintigraphy revealed ectopic parathyroid glands, a mediastinal mass, and an enlarged thymus. The patient underwent thymectomy and mass excision via a median sternotomy. Histopathology was consistent with ectopic parathyroid adenoma and thymolipoma. The serum calcium and parathormone concentrations normalized within 48 hours after surgery.
Keywords:
Adenoma; Hypercalcemia; Hyperparathyroidism; Mediastinal neoplasms; Parathyroid neoplasms; Thymus neoplasms.
© The Author(s) 2016.
MeSH terms
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Adenoma / complications
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Adenoma / diagnostic imaging
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Adenoma / pathology*
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Adenoma / surgery
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Biopsy
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Choristoma* / diagnosis
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Humans
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Hypercalcemia / etiology
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Hyperparathyroidism, Primary / etiology
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Lipoma / diagnostic imaging
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Lipoma / pathology*
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Lipoma / surgery
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Male
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Mediastinal Neoplasms / complications
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Mediastinal Neoplasms / diagnostic imaging
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Mediastinal Neoplasms / pathology*
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Mediastinal Neoplasms / surgery
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Middle Aged
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Neoplasms, Multiple Primary*
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Parathyroid Glands*
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Parathyroid Neoplasms / complications
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Parathyroid Neoplasms / diagnostic imaging
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Parathyroid Neoplasms / pathology*
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Parathyroid Neoplasms / surgery
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Positron Emission Tomography Computed Tomography
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Radiopharmaceuticals
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Sternotomy
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Technetium Tc 99m Sestamibi
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Thymectomy
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Thymus Neoplasms / diagnostic imaging
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Thymus Neoplasms / pathology*
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Thymus Neoplasms / surgery
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Treatment Outcome
Substances
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Radiopharmaceuticals
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Technetium Tc 99m Sestamibi
Supplementary concepts
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Parathyroid cancer, adult