Glycated albumin: from biochemistry and laboratory medicine to clinical practice

Endocrine. 2017 Mar;55(3):682-690. doi: 10.1007/s12020-016-1091-6. Epub 2016 Sep 13.

Abstract

This review summarizes current knowledge about glycated albumin. We review the changes induced by glycation on the properties of albumin, the pathological implications of high glycated albumin levels, glycated albumin quantification methods, and the use of glycated albumin as a complementary biomarker for diabetes mellitus diagnosis and monitoring and for dealing with long-term complications. The advantages and limits of this biomarker in different clinical settings are also discussed.

Keywords: Albumin; Cardiovascular risk; Diabetes mellitus; Diabetes mellitus-related complications; Glycated albumin; Glycation.

Publication types

  • Review

MeSH terms

  • Biomarkers / analysis
  • Diabetes Mellitus / blood
  • Diabetes Mellitus / diagnosis*
  • Glycated Serum Albumin
  • Glycation End Products, Advanced
  • Humans
  • Serum Albumin / analysis*

Substances

  • Biomarkers
  • Glycation End Products, Advanced
  • Serum Albumin
  • Glycated Serum Albumin